19-Hydroxybaccatin III - Names and Identifiers
Name | 19-Hydroxybaccatin III
|
Synonyms | 19-Hydroxybaccatin III 19-HYDROXYBACCATIN III 19-hydroxybaccatin III 19-hydroxylbaccatin III 7,11-Methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-one,6,12b-bis(acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dodecahydro-4,9,11-trihydroxy-4a-(hydroxymethyl)-8,13,13-trimethyl-,(2aR,4S,4aR,6R,9S,11S,12S,12aR,12bS)-
|
CAS | 78432-78-7
|
19-Hydroxybaccatin III - Physico-chemical Properties
Molecular Formula | C31H38O12
|
Molar Mass | 602.63 |
Density | 1.43±0.1 g/cm3(Predicted) |
Melting Point | 173-175 °C(Solv: ethanol (64-17-5)) |
Boling Point | 752.1±60.0 °C(Predicted) |
Solubility | Soluble in water |
Appearance | Solid |
Color | White |
pKa | 12.66±0.70(Predicted) |
Storage Condition | -20°C Freezer |
19-Hydroxybaccatin III - Introduction
19-Hydroxybaccatin III(19-Hydroxybaccatin III) is a naturally occurring compound that belongs to the taxoid derivatives. It is one of the members of the Taxol family, which has multiple hydrogen bond donors and accepators, so it has certain chemical reactivity.
19-Hydroxybaccatin III is mainly used as an intermediate for drugs. It is an important precursor of paclitaxel anti-cancer drugs and can be used to synthesize Pascisol? Drugs such as Paclitaxel and Docetaxel. These drugs have a wide range of applications in cancer therapy and can inhibit tumor growth.
The preparation of 19-Hydroxybaccatin III is generally obtained by extraction from natural sources, and the most commonly used source is Taxol base compound. After extraction, a series of purification and crystallization steps are required to obtain 19-Hydroxybaccatin III with high purity.
Regarding safety information, under normal circumstances, 19-Hydroxybaccatin III is a relatively safe compound, but it still needs to follow laboratory safety procedures. It is a chemical with certain toxicity and irritation. In contact, should pay attention to protective measures, such as wearing gloves, masks and goggles. Avoid inhalation, swallowing or skin contact. In case of careless contact, please rinse the affected parts with plenty of water and seek medical attention in time. When using and handling the compound, follow the appropriate safety guidelines and regulations.
Last Update:2024-04-09 20:49:11